Genetic mechanism discovery key to controlling cell growth in the vinegar fly

A group of researchers has described a key interaction to understanding growth control in the vinegar fly (Drosophila melanogaster). According to the study, the interaction between the transcription factor Cabut and the protein Yorkie (YAP/TAZ in humans) is necessary for tissue and organ regeneration and growth. The study could have biomedical implications as the protein Yorkie is associated with different types of cancer; to avoid the interaction between Cabut and Yorkie could be a potential therapeutic target.



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